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nanofat grafting

What is nanofat grafting?

Nanofat grafting  refers to the very small particles of fat that are specifically filtered and emulsified and used for areas to be  injected, in this process the harvested fat filtered and emulsified  to obtain nano-particles.This emulsion contain high percentage of stem cells,endothelial cells, monocytes, macrophages and granulocytes which activation of stem cells increases collagen production. The major effect of nanofat injection is  tissue regeneration and rejuvenation especially  for correction of undereye circles and improvement of injured skin. During processing and filtering  harvested materials many fat cells  die (cell apoptosis) so nanofat injection do not have the capacity to build up a significant  volume. In fact, because of the lack of adipocytes, the volumetric effect of nanofat is obviously very limited. On the other hand microfat grafting has been used to build up large volumes and tissue enhancement in the face, breasts or buttocks. Therefore, the indications for nanofat injection are different when compared with microfat grafting. nanofat grafting undereyes

nanofat grafting 

Nanofat grafting under eyes

The main problem after nanofat transfer to under eyes are swelling, bruising, redness at injection site and some edema which may last up to 2-3 weeks to resolve. During 48 hours after fat grafting it is recommended to cool down the area and sleep in semi sitting position for fastest recovery and stay away from blood thinning drugs such as omega 3, ibuprofen for a few weeks.When properly performed, a nanofat transfer can last a long time.

Nanofat grafting article written by Dr. Mosaferian:


Nanofat injection cost

Treatment of facial aging changes with nanofat  injections must  be carefully individualized to match each patient’s aesthetic needs and desires. An individualized surgical plan is developed which addresses each patient’s specific concerns and needs.
Therefore, the price of a facial fat grafting will depend on exactly what each person needs and the time required to perform surgery.

fat tansfer before after
fat tansfer

fat injections side effects

Fat injections side effects are few, rare, and minimal. Soreness and swelling are most  experienced complications. Infection presenting  may affect graft survival. Viral infections or herpes infection have also been reported at the site of cannula entry.

Fat embolism, particularly if injected with sharp needle.Blindness may result as a direct consequence of needle puncture and intracapsular trauma or pressure related retinal artery thrombosis.Cyst formation is more common when a large amount of fat is transferred.Skin necrosis and sinus formation may result from overfilling or over augmentation of the desired site.Compression atrophy may result from over augmentation with associated avascular necrosis due to excessive pressure on vasculature which can result in arterial or venous thrombosis.

Haematoma or seroma formation may occur more commonly if blunt cannulae are not used and when the patient is on other anticoagulant medication or supplements providing an anticoagulant effect.

Nanofat prp

In  nanofat transfer, the addition of platelet rich plasma (PRP) can be used to optimize the results by vascular proliferation around gafted fat cells. Just like the fat itself, the PRP is harvested from the patient’s own body, and then spun to concentrate the wound-healing platelets. The use of s PRP greatly increases the proportion of fat cells that survive the traumatic transfer process, ensuring the most efficient use of tissue and the enhancing the results.

Nanofat grafting certificate
Nanofat grafting certificate

Please click on the following clip to watch transforming of Microfat to Nanofat

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